{"id":15841,"date":"2025-04-14T09:41:36","date_gmt":"2025-04-14T09:41:36","guid":{"rendered":"https:\/\/www.watanserb.com\/en\/?p=15841"},"modified":"2025-04-14T09:41:36","modified_gmt":"2025-04-14T09:41:36","slug":"breakthrough-saliva-test-for-prostate-cancer-detects-more-high-risk-cases-than-traditional-methods","status":"publish","type":"post","link":"https:\/\/www.watanserb.com\/en\/2025\/04\/14\/breakthrough-saliva-test-for-prostate-cancer-detects-more-high-risk-cases-than-traditional-methods\/","title":{"rendered":"Breakthrough Saliva Test for Prostate Cancer Detects More High-Risk Cases Than Traditional Methods"},"content":{"rendered":"<p><em><strong>Watan<\/strong><\/em>-A group of researchers has developed a home test for detecting prostate cancer that may outperform current screening methods.<\/p>\n<article class=\"text-token-text-primary w-full\" dir=\"auto\" data-testid=\"conversation-turn-2\" data-scroll-anchor=\"true\">\n<div class=\"text-base my-auto mx-auto py-5 [--thread-content-margin:--spacing(4)] @[37rem]:[--thread-content-margin:--spacing(6)] @[70rem]:[--thread-content-margin:--spacing(12)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:32rem] @[34rem]:[--thread-content-max-width:40rem] @[64rem]:[--thread-content-max-width:48rem] mx-auto flex max-w-(--thread-content-max-width) flex-1 text-base gap-4 md:gap-5 lg:gap-6 group\/turn-messages focus-visible:outline-hidden\" tabindex=\"-1\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"relative flex-col gap-1 md:gap-3\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"87f1559e-0ffe-4fc4-aff5-4976e4e754b1\" data-message-model-slug=\"gpt-4o\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light\">\n<p class=\"\" data-start=\"127\" data-end=\"322\">Currently, doctors use MRI scans, biopsies, and a blood test called the Prostate-Specific Antigen (PSA) test to detect prostate conditions such as prostate cancer or benign prostatic hyperplasia.<\/p>\n<p class=\"\" data-start=\"324\" data-end=\"608\">However, the developers of the new test\u2014which relies on saliva samples\u2014have stated that it is better than traditional methods for detecting the disease. It reduces the number of false positives and detects a higher proportion of aggressive cancer cases compared to conventional tests.<\/p>\n<figure id=\"attachment_11187\" aria-describedby=\"caption-attachment-11187\" style=\"width: 972px\" class=\"wp-caption alignleft\"><img decoding=\"async\" class=\"wp-image-11187 size-full\" src=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/01\/hhhhhhh5.jpg\" alt=\"A new &quot;Polygenic Risk Score&quot; test developed in the UK may revolutionize early prostate cancer detection using a simple home saliva sample.\" width=\"972\" height=\"624\" srcset=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/01\/hhhhhhh5.jpg 972w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/01\/hhhhhhh5-300x193.jpg 300w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/01\/hhhhhhh5-768x493.jpg 768w\" sizes=\"(max-width: 972px) 100vw, 972px\" \/><figcaption id=\"caption-attachment-11187\" class=\"wp-caption-text\">Cancer prevention tips<\/figcaption><\/figure>\n<h3 data-start=\"173\" data-end=\"228\"><strong data-start=\"173\" data-end=\"228\">New Saliva Test Detects Hidden Prostate Cancer Risk<\/strong><\/h3>\n<p class=\"\" data-start=\"610\" data-end=\"830\">According to The Independent (UK), the new test was developed by researchers at The Institute of Cancer Research in London and The Royal Marsden NHS Foundation Trust. They have named it the \u201cPolygenic Risk Score\u201d test.<\/p>\n<p class=\"\" data-start=\"832\" data-end=\"1034\">The test analyzes saliva to assess 130 genetic variants known to be associated with an increased risk of prostate cancer, helping to determine whether a person is at high risk of developing the disease.<\/p>\n<p class=\"\" data-start=\"1036\" data-end=\"1112\">Researchers tested the method on 6,300 men aged between 55 and 69 in the UK.<\/p>\n<p class=\"\" data-start=\"1114\" data-end=\"1216\">During the study, the test identified around 745 men (12%) as having a high risk of developing cancer.<\/p>\n<p class=\"\" data-start=\"1218\" data-end=\"1361\">These men were invited to undergo <a href=\"https:\/\/www.watanserb.com\/en\/2025\/03\/25\/skipping-prostate-screenings-increases-cancer-death-risk-by-45-major-study-finds\/\">prostate<\/a> cancer screening, including an MRI scan and a biopsy. About 468 of them responded to the invitation.<\/p>\n<p class=\"\" data-start=\"1363\" data-end=\"1490\">Among those, traditional screening methods <a href=\"https:\/\/www.watanserb.com\/en\/2025\/01\/09\/ai-boosts-breast-cancer-detection-accuracy-in-real-world-screening\/\">detected<\/a> prostate cancer in 187 men, of which 103 cases were considered \u201chigh risk.\u201d<\/p>\n<figure id=\"attachment_14805\" aria-describedby=\"caption-attachment-14805\" style=\"width: 1024px\" class=\"wp-caption alignleft\"><img decoding=\"async\" class=\"wp-image-14805 size-large\" src=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966-1024x576.jpg\" alt=\"New PSA Test Detects Aggressive Prostate Cancer Cases Early\" width=\"1024\" height=\"576\" srcset=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966-1024x576.jpg 1024w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966-300x169.jpg 300w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966-768x432.jpg 768w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966-390x220.jpg 390w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/03\/78966.jpg 1440w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption id=\"caption-attachment-14805\" class=\"wp-caption-text\">cancer prevention<\/figcaption><\/figure>\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"349b782e-c79e-45fe-9d26-0e33b3745ba0\" data-message-model-slug=\"gpt-4o-mini\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light\">\n<h3 data-start=\"0\" data-end=\"61\">&#8220;New PSA Test Detects Aggressive Prostate Cancer Cases Early&#8221;<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\">\n<div class=\"mx-auto\">\n<div>\n<div class=\"inline-flex rounded-xl border border-gray-100 dark:border-gray-700\">\n<div class=\"text-token-text-secondary flex items-center justify-center gap-4 px-4 py-3 text-sm\">Researchers then conducted PSA tests on the 187 men, and the test showed that 118 of them had \u201cnormal\u201d results and would not have been flagged for further testing.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p data-start=\"1657\" data-end=\"1804\">\n<p class=\"\" data-start=\"1657\" data-end=\"1804\">The researchers noted that the cancer \u201cwould not have been detected\u201d in a large portion of these participants using the current diagnostic pathway.<\/p>\n<p class=\"\" data-start=\"1806\" data-end=\"1992\">They wrote in their study that \u201cthe test identified cancer patients who would likely have been missed by traditional methods and detected a higher proportion of aggressive cancer cases.\u201d<\/p>\n<p class=\"\" data-start=\"1994\" data-end=\"2223\">Professor Ros Eeles, from the Institute of Cancer Research in London and a co-author of the study, said: \u201cThanks to this simple and relatively inexpensive test, we could change the course of prostate cancer and treat it earlier.\u201d<\/p>\n<p class=\"\" data-start=\"2225\" data-end=\"2379\">Prostate cancer is among the most common types of <a href=\"https:\/\/www.watanserb.com\/en\/2025\/01\/24\/the-alarming-rise-of-cancer-among-young-people-causes-concerns-and-prevention\/\">cancer<\/a> in men, although it often grows slowly and may not cause noticeable symptoms in its early stages.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Watan-A group of researchers has developed a home test for detecting prostate cancer that may outperform current screening methods. Currently, doctors use MRI scans, biopsies, and a blood test called the Prostate-Specific Antigen (PSA) test to detect prostate conditions such as prostate cancer or benign prostatic hyperplasia. However, the developers of the new test\u2014which relies &hellip;<\/p>\n","protected":false},"author":1,"featured_media":10645,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[4438,4801,4802],"class_list":["post-15841","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle","tag-prostate-cancer","tag-prostate-specific-antigen","tag-prostatic-hyperplasia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Breakthrough Saliva Test for Prostate Cancer Detects More High-Risk Cases Than Traditional Methods - Watan<\/title>\n<meta name=\"description\" content=\"Researchers in the UK have developed a groundbreaking saliva-based test for prostate cancer that outperforms traditional methods\" \/>\n<meta name=\"robots\" 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