{"id":13083,"date":"2025-02-17T13:07:42","date_gmt":"2025-02-17T13:07:42","guid":{"rendered":"https:\/\/www.watanserb.com\/en\/?p=13083"},"modified":"2025-02-17T13:07:42","modified_gmt":"2025-02-17T13:07:42","slug":"bahrain-achieves-historic-medical-breakthrough-with-gene-editing-therapy","status":"publish","type":"post","link":"https:\/\/www.watanserb.com\/en\/2025\/02\/17\/bahrain-achieves-historic-medical-breakthrough-with-gene-editing-therapy\/","title":{"rendered":"Bahrain Achieves Historic Medical Breakthrough with Gene-Editing Therapy"},"content":{"rendered":"<p><em><strong>Watan<\/strong><\/em>-The Bahrain Oncology Center has accomplished a pioneering medical breakthrough by successfully treating a patient with sickle cell anemia using Casgevy (Exagamglogene Autotemcel)\u2014a gene-editing therapy based on CRISPR technology for bone marrow transplantation.<\/p>\n<p>This patient is the first outside the United States to be publicly confirmed as having received the treatment successfully, positioning Bahrain as a global leader in precision medicine and innovative healthcare solutions.<\/p>\n<div class=\"flex max-w-full flex-col flex-grow\">\n<div class=\"min-h-8 text-message flex w-full flex-col items-end gap-2 whitespace-normal break-words text-start [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"64b24308-0f09-4bf4-9e86-6d945a0e0157\" data-message-model-slug=\"gpt-4o\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light\">\n<p data-start=\"584\" data-end=\"895\">Bahraini Minister of Health, Dr. Jalila Hassan, stated that this achievement &#8220;reflects Bahrain\u2019s commitment to integrating global medical innovations into its national health strategy and fostering partnerships between institutions to ensure broad access to life-changing treatments for all citizens.&#8221;<\/p>\n<h3 data-start=\"17\" data-end=\"91\"><strong data-start=\"17\" data-end=\"89\">Bahrain Advances Precision Medicine with Groundbreaking Gene Therapy<\/strong><\/h3>\n<p data-start=\"897\" data-end=\"1329\">This milestone marks a significant leap in precision medicine in Bahrain and the region. It follows Bahrain&#8217;s December 2, 2023, recognition as the second country in the world and the first in the Middle East to approve Casgevy for treating sickle cell disease (SCD) and transfusion-dependent beta-thalassemia (TDT) after undergoing a comprehensive assessment of safety, quality, and efficacy standards.<\/p>\n<figure id=\"attachment_13085\" aria-describedby=\"caption-attachment-13085\" style=\"width: 1024px\" class=\"wp-caption alignleft\"><img decoding=\"async\" class=\"wp-image-13085 size-large\" src=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain-1024x756.jpg\" alt=\"Royal Medical Services and Bahrain Oncology Center pioneer gene-editing treatment for sickle cell anemia.\" width=\"1024\" height=\"756\" srcset=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain-1024x756.jpg 1024w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain-300x222.jpg 300w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain-768x567.jpg 768w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain.jpg 1200w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption id=\"caption-attachment-13085\" class=\"wp-caption-text\">gene-editing therapy<\/figcaption><\/figure>\n<p data-start=\"1331\" data-end=\"1790\">The transplantation process involves stimulating the patient&#8217;s bone marrow to produce large quantities of stem cells using specialized injections. These stem cells are then genetically modified to produce red blood cells containing a functional form of hemoglobin similar to that found in healthy individuals. The final stage involves reintroducing the modified cells into the patient\u2019s bloodstream after rigorous quality and safety testing.<\/p>\n<h3 data-start=\"17\" data-end=\"75\"><strong data-start=\"17\" data-end=\"73\">Bahrain Strengthens Leadership in Precision Medicine<\/strong><\/h3>\n<p data-start=\"1792\" data-end=\"2365\">Sheikh Fahd bin Salman Al Khalifa, Commander of the Royal Medical Services, expressed pride in Bahrain\u2019s role as a leader in regional medical innovation:&#8221;Our success in delivering sickle cell anemia treatment through bone marrow transplantation using gene editing technology reflects Bahrain\u2019s commitment to providing cutting-edge medical solutions and strengthening its regional leadership in precision medicine. This treatment offers new hope for patients with genetic blood disorders and underscores Bahrain\u2019s growing role in healthcare innovation.&#8221;<\/p>\n<figure id=\"attachment_13086\" aria-describedby=\"caption-attachment-13086\" style=\"width: 1000px\" class=\"wp-caption alignleft\"><img decoding=\"async\" class=\"wp-image-13086 size-full\" src=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain1.jpg\" alt=\"Bahrain makes history as the first country outside the U.S. to successfully treat sickle cell disease using Casgevy, a CRISPR-based gene therapy\" width=\"1000\" height=\"545\" srcset=\"https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain1.jpg 1000w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain1-300x164.jpg 300w, https:\/\/www.watanserb.com\/en\/wp-content\/uploads\/2025\/02\/barain1-768x419.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><figcaption id=\"caption-attachment-13086\" class=\"wp-caption-text\">Bahrain Advances Precision Medicine with Groundbreaking Gene Therapy<\/figcaption><\/figure>\n<p data-start=\"2367\" data-end=\"2855\" data-is-last-node=\"\">Meanwhile, Dr. Edward Rowland, CEO of the Bahrain Oncology Center, emphasized that this achievement highlights the center\u2019s &#8220;commitment to integrating advanced technology with global expertise.&#8221; He added that the success was made possible &#8220;after obtaining international accreditation for bone marrow transplantation services, reaffirming our dedication to enhancing available health solutions through precision medicine and collaboration with leading global institutions.&#8221;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mb-2 flex gap-3 empty:hidden -ml-2\">\n<div class=\"items-center justify-start rounded-xl p-1 flex\">\n<div class=\"flex items-center\"><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Watan-The Bahrain Oncology Center has accomplished a pioneering medical breakthrough by successfully treating a patient with sickle cell anemia using Casgevy (Exagamglogene Autotemcel)\u2014a gene-editing therapy based on CRISPR technology for bone marrow transplantation. This patient is the first outside the United States to be publicly confirmed as having received the treatment successfully, positioning Bahrain as &hellip;<\/p>\n","protected":false},"author":1,"featured_media":13084,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[132,3972,3973],"class_list":["post-13083","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-bahrain","tag-crispr-gene-therapy","tag-sickle-cell-treatment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Bahrain Achieves Historic Medical Breakthrough with Gene-Editing Therapy - Watan<\/title>\n<meta name=\"description\" content=\"Bahrain has become the first country outside the U.S. to successfully treat a sickle cell patient using Casgevy.. gene-editing 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